Cognitive impairment due to exposure to mixture of organic solvents in hospital pathologists In Mexico City

Introduction
Introduction
Different neurobehavioral effects have been reported in industrial and hospital workers from their chronic exposure to organic solvents. This research studies workers from the pathology department, that are exposed throughout the workday to a mixture of Formaldehyde, Xylene, Glutaraldehyde, resins and paraffin, to determine the type of predominant neurobehavioral effects present and the labor variables associated with these effects.

Methods
Methodology
A cross-sectional comparative study of 39 workers divided in 3 sub-groups, 10 directly exposed, 10 indirectly exposed and 19 unexposed. We applied a neurobehavioral tests battery based in the WHO proposal. Information on age, sex, age, smoking, alcohol, and body mass index was collected. The SPSS 19 was used to analyze the data. The Chi-square test, Mann Whitney test and linear regression analysis were used.

Results
Results
The most affected neurobehavioral process were the evocative language ( p = 0.001), visuospatial memory ( p = 0.06) and auditory memory ( p = 0.004). The regression showed no association by age, sex or age in the targeted language, this was mainly associated with the exposure and BMI. Only the deterioration of visuospatial memory was also affected by smoking and the auditory memory was associated with the exposure, age group and seniority (R =0.346, p = 0.002).

Discussion
Discussion
This study verifies the reported in the literature, organic solvents have repercussions for higher cognitive processes. The observed effects in these qualified workers may expresses a high cognitive deterioration in the future. Hence, it is important to prevent these problems and maintaining these workplaces in good conditions.