Evaluation of carcinogenic risk, mutagenic and reproductive toxicant pesticides used in banana plantations in Guadeloupe

Introduction
The banana cultivation is under heavy pest pressure in Guadeloupe. This causes extensive use of pesticides.
The objective is to assess the risk of cancer, mutagenic and toxic to reproduction for farm workers who use pesticides in banana plantations.

Methods
We identified and analyzed 130 data sheets safety of pesticides sold to farmers by a cooperative (95% of products used in banana plantations). MSDS Styltime software allowed us to identify the presence or absence of risk Carcinogen, Mutagen, Reprotoxic. We also verified the existence of a limit value for occupational exposure, and a biological limit value. We have considered the European classification and the International Centre for Research on Cancer (IARC)

Results
2 herbicides and 2 fungicides are classified as carcinogens by IARC as possible.
1Herbicide is classified as a C2:
1 acaricidal is classed C3 and 2 fungicides are classified C3. and IIB by IARC
1 fungicide and 1 herbicide are classified M2.
2 fungicides, 1 insecticide and 1 herbicide are classified R2.
1 fungicide and 1 insecticide are classified R3
With some substances, it is possible to take samples of the atmosphere to look at values occupational exposure limits (OELs) for a short and medium term. These OELs are only indicative and not binding.
We can also make a biological monitoring in the order to assay metabolites in
blood or urine and have a biological exposure index with some substances.

Discussion
For the first time in Guadeloupe, a risk assessment of pesticides' CMR was performed as part of a multidisciplinary working (Occupational, Toxicologist and assistant health). A total of 130 products, 12 products are carcinogenic, mutagenic or toxic to reproduction: 7 CMR2 and 5 CMR3. This work will enable the physician to steer Labour metrology on the workplace and the specific requirement of additional tests at the medical visit.