The guideline for reading the CT images with mesothelioma

Tamura, Taro

Wednesday, March 21, 2012: 17:40

Costa Maya 1 (Cancun Center)

Taro Tamura, Department of Environmental Health, University Of Fukui School Of Medicine, Eiheiji, Japan

Zhou Huashi, Department of Environmental Health, University Of Fukui School Of Medicine, Eiheiji, Japan

Narufumi Suganuma, Department of Environmental Medicine, Kochi University School of Medicine, Kochi, Japan

Norio Kurumatani, Department of Community Health and Epidemiology, Nara Medical UniversitySchool of Medicine, Kashihara, Japan

Seong-Kyu Kang, Department of Environmental Health, Osaka Prefectural Institute of Public Health, Osaka, Japan

Ponglada Subhannachart, Academic Affairs Cluster, Central Chest Institute of Thailand, NONTHABURI, Thailand

Chomphunut Vijitsanguan, Department of Radiology, Central Chest Institute of Thailand, NONTHABURI, Thailand

Weeraya Noisiri, Department of Radiology, Central Chest Institute of Thailand, NONTHABURI, Thailand

Yukinori Kusaka, Department of Environmental Health, University Of Fukui School Of Medicine, Eiheiji, Japan

Introduction
We studied the CT images of 22 cases with malignant mesothelioma (MM), which were confirmed being pathologically and immuno-histo-chemically. International experts read the films individually, and we choose the typical cases. We agreed typical features about MM. Finally we made the guideline and reference images about MM. The selected features are Unilateral pleural effusion, Nodular pleural thickening, Interlobar fissure thickening, Mediastinal pleural thickening, Tumoral encasement of lung, Calcified plaque engulfment, Invasion, Diminished lung, Contracted hemithorax, Pleural mass, and others.

Methods
Three Thailand radiologists read the 22 subject CT films of mesothelioma (17 films were high probability) and non-mesothelioma (5 films ware low probability) independently, twice, before studying the guideline and reference films, and after studying them. We analyze the result about the features and probability.

Results
Sensitivity and Specificity of 1st time reading was 47.06% and 60% by Radiologist 1, 64.71% and 60% by Radiologist 2, 41.8% and 100%. Their crude agreement was 50%, 63.63%, and 54.55%. Sensitivity and Specificity of 2nd time reading was 76.7% and 40% by Radiologist 1, 88.24% and 60% by Radiologist 2, 58.82% and 100% by Radiologist 3. Their crude agreement was 68.18%, 68.18%, and 68.18%.

Discussion
2nd time crude agreement of all readers were better than 1st time results.
The reference CT images and guideline will help radiologists and other physicians identify mesothelioma.

A1771 The guideline for reading the CT images with mesothelioma